Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10329102 | 0.79 | BACE1 (0.44) | — | |
| SCHEMBL10328570 | 0.77 | MAPT (0.31) | — | |
| SCHEMBL10328573 | 0.76 | HCAR3 (0.32) | — | |
| SCHEMBL10328574 | 0.74 | BACE1 (0.40) | — | |
| SCHEMBL10328562 | 0.74 | BACE1 (0.30) | — | |
| SCHEMBL10328577 | 0.72 | BACE1 (0.33) | — | |
| SCHEMBL10329022 | 0.72 | — | — | |
| SCHEMBL10328565 | 0.72 | BACE1 (0.39) | — | |
| SCHEMBL10328566 | 0.71 | — | — | |
| SCHEMBL13413 | 0.71 | BACE1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3034080-A1 | IMINOTHIADIAZINE DIOXIDE COMPOUNDS AS BACE INHIBITORS, COMPOSITIONS, AND THEIR USE | Merck Sharp & Dohme Corp. (US) | 2016-06-22 | — | — | EP | disclosed |