Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108095 | 0.88 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL106213 | 0.82 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL17850272 | 0.80 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL107332 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL17850254 | 0.79 | P2RX7 (0.78) | P2RX7 | |
| SCHEMBL17850245 | 0.79 | P2RX7 (0.77) | P2RX7 | |
| SCHEMBL17850273 | 0.79 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL110564 | 0.77 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL107128 | 0.77 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL110571 | 0.77 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424869-B1 | 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LTD (GB) | 2016-06-22 | — | — | EP | disclosed |