Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850254 | 0.88 | P2RX7 (0.78) | P2RX7TACR3 | |
| SCHEMBL106922 | 0.85 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL17850218 | 0.83 | P2RX7 (0.74) | P2RX7TACR3 | |
| SCHEMBL108686 | 0.81 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL17850242 | 0.81 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL9972034 | 0.80 | P2RX7 (0.84) | P2RX7 | |
| SCHEMBL9930361 | 0.78 | P2RX7 (1.00) | P2RX7TACR3 | |
| SCHEMBL108975 | 0.78 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL107391 | 0.77 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL108781 | 0.77 | P2RX7 (0.82) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424869-B1 | 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-a]PYRAZINE DERIVATIVES AS P2X7 MODULATORS | GLAXO GROUP LTD (GB) | 2016-06-22 | — | — | EP | disclosed |