Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11402474 | 0.84 | MEN1 (0.52) | MEN1KMT2ATP53HRH3HTT | |
| SCHEMBL15317757 | 0.83 | MET (0.51) | METMEN1KMT2ATP53 | |
| SCHEMBL4054492 | 0.78 | HTT (0.62) | MEN1KMT2ATP53HTT | |
| SCHEMBL2466706 | 0.78 | MET (0.58) | METMEN1KMT2ATP53 | |
| SCHEMBL10195704 | 0.78 | PDE4B (0.50) | MEN1KMT2ATP53HTT | |
| SCHEMBL4061176 | 0.77 | MAPT (0.52) | METMEN1KMT2ATP53HRH3 | |
| Bromide SCHEMBL5751833 | 0.77 | HTT (0.61) | MEN1KMT2ATP53HTT | |
| SCHEMBL13561689 | 0.77 | MET (0.74) | METMEN1KMT2A | |
| SCHEMBL24035608 | 0.75 | MEN1 (0.52) | MEN1KMT2ATP53HRH3HTT | |
| SCHEMBL10194702 | 0.75 | KDM4E (0.52) | MEN1KMT2ATP53HRH3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |