Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 12/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850412 | 0.74 | ESRRA (0.48) | ESRRANOTUMGPR119 | |
| SCHEMBL10194980 | 0.71 | HTR2C (0.42) | HTR2CNOTUMP2RY14ADRA2AADRA2B | |
| SCHEMBL10195750 | 0.66 | ESRRA (0.62) | ESRRA | |
| SCHEMBL10196894 | 0.66 | ESRRA (0.56) | ESRRA | |
| SCHEMBL10196715 | 0.66 | ESRRA (0.53) | ESRRASIGMAR1 | |
| SCHEMBL10195780 | 0.66 | ESRRA (0.44) | ESRRA | |
| SCHEMBL10194711 | 0.65 | ESRRA (0.60) | ESRRA | |
| SCHEMBL14321224 | 0.65 | HTR2C (0.61) | HTR2CNOTUM | |
| SCHEMBL27984001 | 0.65 | ESRRA (1.00) | ESRRANOTUM | |
| SCHEMBL613612 | 0.64 | HTR2C (1.00) | HTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655357-B1 | INDAZOLYL TRIAZOLE DERIVATIVES AS IRAK INHIBITORS | MERCK SERONO SA (CH) | 2016-06-22 | — | — | EP | disclosed |