Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25090004 | 0.76 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL20055612 | 0.76 | THRB (0.35) | THRBMEN1KMT2A | |
| SCHEMBL23370851 | 0.71 | — | — | |
| SCHEMBL5316919 | 0.69 | DPP4 (0.31) | — | |
| SCHEMBL17010885 | 0.68 | — | — | |
| SCHEMBL28633603 | 0.68 | — | — | |
| SCHEMBL10518543 | 0.67 | KDM4E (0.39) | — | |
| SCHEMBL18433962 | 0.67 | — | — | |
| SCHEMBL6941782 | 0.67 | — | — | |
| SCHEMBL7854115 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643299-B1 | BIPYRIDINE SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES OR CONDITIONS | NOSCIRA SA (ES) | 2016-06-22 | — | — | EP | disclosed |