Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29012476 | 1.00 | MEN1 (0.58) | MEN1KMT2AL3MBTL1ALPLGAA | |
| SCHEMBL569726 | 0.88 | MEN1 (0.59) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL1965809 | 0.88 | CA12 (0.53) | L3MBTL1CA1CA2MAPTALDH1A1 | |
| SCHEMBL17699412 | 0.86 | MEN1 (0.52) | MEN1KMT2AL3MBTL1ALPLGAA | |
| SCHEMBL18844819 | 0.85 | UTS2R (0.48) | MEN1KMT2ACA1CA2LMNA | |
| SCHEMBL17965728 | 0.84 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ALPLGAA | |
| SCHEMBL1798327 | 0.84 | MEN1 (0.55) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL15710024 | 0.84 | MEN1 (0.55) | MEN1KMT2AL3MBTL1HTTCA1 | |
| SCHEMBL4578229 | 0.84 | MEN1 (0.55) | MEN1KMT2AL3MBTL1CA1CA2 | |
| SCHEMBL17699407 | 0.84 | MEN1 (0.49) | MEN1KMT2AL3MBTL1ALPLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771320-B1 | CYCLOHEXYLAMINES | ENDO PHARMACEUTICALS INC (US) | 2016-06-22 | — | — | EP | disclosed |