SCHEMBL17699412

SCHEMBL17699412

CCC(CC(C)OC(=O)c1ccc(C(C)(C)C)cc1)OC(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
HTT P42858 1/20 0.42
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
GRIA4 P48058 1/20 0.41
TDP1 Q9NUW8 2/20 0.40
MAPT P10636 2/20 0.40
NR1H4 Q96RI1 2/20 0.39
EPHX2 P34913 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
ALOX15 P16050 1/20 0.39
APEX1 P27695 1/20 0.39
MAPK1 P28482 1/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17699393 0.91 MEN1 (0.47) MEN1KMT2AL3MBTL1ALPLGAA
SCHEMBL569726 0.88 MEN1 (0.59) MEN1KMT2AL3MBTL1CA1CA2
SCHEMBL29012476 0.86 MEN1 (0.58) MEN1KMT2AL3MBTL1ALPLGAA
SCHEMBL17850552 0.86 MEN1 (0.58) MEN1KMT2AL3MBTL1ALPLGAA
SCHEMBL4578229 0.84 MEN1 (0.55) MEN1KMT2AL3MBTL1CA1CA2
SCHEMBL17699431 0.84 CYP4F2 (0.46) L3MBTL1CA1CA2TDP1MAPT
SCHEMBL19570771 0.82 MAPT (0.55) MEN1KMT2AL3MBTL1CA1CA2
SCHEMBL569951 0.82 LMNA (0.49) MEN1KMT2AHTTALDH1A1LMNA
SCHEMBL17699357 0.80 CYP4A11 (0.50) KMT2AL3MBTL1GAACA1CA2
SCHEMBL17699436 0.80 CYP4F2 (0.43) L3MBTL1CA1CA2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9751960-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-09-05 US claimed
US-20160115257-A1 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-04-28 US claimed
US-9751960-B2 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-09-05 US disclosed
US-20160115257-A1 Catalyst component for olefin polymerization, catalyst, and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-04-28 US disclosed