SCHEMBL1785109

SCHEMBL1785109

CCCCN(Cl)CCCC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.42
CA1 P00915 5/20 0.42
CA9 Q16790 5/20 0.42
TSHR P16473 4/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CA2 P00918 3/20 0.39
DNM1 Q05193 3/20 0.38
THRB P10828 1/20 0.38
ALDH1A1 P00352 4/20 0.36
ALDH2 P05091 1/20 0.36
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP8 P22894 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6233207 0.97 DNM1 (0.41) CA12CA1CA9TSHRLMNA
Water SCHEMBL5077362 0.97 CA12 (0.40) CA12CA1CA9TSHRLMNA
SCHEMBL28756631 0.94 DNM1 (0.48) CA12CA1CA9TSHRLMNA
SCHEMBL10749508 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL9463621 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL10748735 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL5694373 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL10454324 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL10529077 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA
SCHEMBL28072813 0.87 DNM1 (0.55) CA12CA1CA9TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3013352-B1 MECHANISM AND DRUG TARGETS FOR REDUCING CELL EDEMA (NEUROPROTECTION) AND CYTOPLASMIC EXCITABILITY IN ASTROCYTES IN NORMAL AND PATHOLOGICAL STATES CELICA BIOMEDICAL (SI) 2018-09-05 EP claimed
US-20160139112-A1 MECHANISM AND DRUG TARGETS FOR REDUCING CELL EDEMA (NEUROPROTECTION) AND CYTOPLASMIC EXCITABILITY IN ASTROCYTES IN NORMAL AND PATHOLOGICAL STATES CELICA BIOMEDICAL (SI) 2016-05-19 US claimed
EP-3013352-A1 MECHANISM AND DRUG TARGETS FOR REDUCING CELL EDEMA (NEUROPROTECTION) AND CYTOPLASMIC EXCITABILITY IN ASTROCYTES IN NORMAL AND PATHOLOGICAL STATES Celica BIOMEDICAL (SI) 2016-05-04 EP claimed
WO-2014206948-A1 MECHANISM AND DRUG TARGETS FOR REDUCING CELL EDEMA (NEUROPROTECTION) AND CYTOPLASMIC EXCITABILITY IN ASTROCYTES IN NORMAL AND PATHOLOGICAL STATES CELICA D.O.O. (SI) 2014-12-31 WO claimed
EP-2818177-A1 Mechanism and drug targets for reducing cell edema (neuroprotection) and cytoplasmic excitability in astrocytes in normal and pathological states Celica, D.O.O. (SI) 2014-12-31 EP claimed
CN-112470045-B Optical filter and display device 住友化学株式会社 2023-08-08 CN disclosed
CN-112470045-A Optical filter and display device 住友化学株式会社 2021-03-09 CN disclosed
CN-112469695-A Compound and method for producing same 住友化学株式会社 2021-03-09 CN disclosed
WO-2020022134-A1 COMPOUND AND METHOD FOR PRODUCING SAME 住友化学株式会社 2020-01-30 WO disclosed
WO-2020022135-A1 OPTICAL FILTER AND DISPLAY DEVICE 住友化学株式会社 2020-01-30 WO disclosed
EP-3013352-B1 MECHANISM AND DRUG TARGETS FOR REDUCING CELL EDEMA (NEUROPROTECTION) AND CYTOPLASMIC EXCITABILITY IN ASTROCYTES IN NORMAL AND PATHOLOGICAL STATES CELICA BIOMEDICAL (SI) 2018-09-05 EP disclosed
US-9970924-B2 Mechanism and drug targets for reducing cell edema (neuroprotection) and cytoplasmic excitability in astrocytes in normal and pathological states CELICA BIOMEDICAL (SI) 2018-05-15 US disclosed
US-6828395-B1 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-4931562-A Piperidines LION CORPORATION (JP) 1990-06-05 US disclosed
US-4820437-A MIXTURE OF HYDROGEN PEROXIDE AND NITROGEN CONTAINING HETEROCYCLIC ACTIVATORS LION CORPORATION (JP) 1989-04-11 US disclosed
EP-0071839-B1 AROMATIC DIISOCYANATES HAVING N,N-DISUBSTITUTED SULFONAMIDO GROUPS, THEIR METHOD OF PREPARATION AND THEIR USE IN THE PREPARATION OF POLYURETHANES BAYER AG (DE) 1985-09-25 EP disclosed
US-4496491-A Aromatic diisocyanates containing N,N-disubstituted sulfonamide groups and processes for their production BAYER AKTIENGESELLSCHAFT (DE) 1985-01-29 US disclosed
EP-0071839-A1 Aromatic diisocyanates having N,N-disubstituted sulfonamido groups, their method of preparation and their use in the preparation of polyurethanes BAYER AG (DE) 1983-02-16 EP disclosed
US-4013758-A PROCESS FOR PREPARING HYDRAZINES OSBORG HANS 1977-03-22 US disclosed
US-3966769-A Sulfonyl compounds CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed