Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 4/20 | 0.39 |
| ▸ | CES1 | P23141 | 4/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL1072571 | 0.92 | TSHR (0.48) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29006821 | 0.87 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1783310 | 0.87 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4576581 | 0.83 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11228092 | 0.83 | TSHR (0.58) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27522267 | 0.81 | DAO (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1081588 | 0.81 | DAO (0.47) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28321148 | 0.80 | TSHR (0.50) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28737090 | 0.80 | TSHR (0.54) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL1072577 | 0.79 | DAO (0.41) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290624-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290623-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-118290625-A | Polypropylene and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-117756970-A | Catalyst for butene-1 polymerization and application thereof | 中国石油化工股份有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-114478846-B | Carrier of catalyst with olefin polymerization catalyzing function, preparation method and application thereof, olefin polymerization catalyst and application thereof | 中国石油化工股份有限公司 | 2023-09-08 | — | — | CN | claimed |
| CN-115975084-A | Catalyst component for olefin polymerization, catalyst and application | 中国石油化工股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-113444189-A | Catalyst for olefin polymerization and application thereof | 中国石油化工股份有限公司 | 2021-09-28 | — | — | CN | claimed |
| EP-3059264-B1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEM CORP (CN) | 2018-12-26 | — | — | EP | claimed |
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| US-20160264694-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2016-09-15 | — | — | US | claimed |
| EP-3059264-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME | China Petroleum&Chemical Corporation (CN) | 2016-08-24 | — | — | EP | claimed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | claimed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | claimed |
| CN-117924548-A | Catalyst component for olefin polymerization, preparation method, catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2024-04-26 | — | — | CN | disclosed |
| US-20230391902-A1 | MAGNESIUM-BASED SOLID AND CATALYST COMPONENT HAVING MULTIMODAL PORE DISTRIBUTION, AND PREPARATION METHODS THEREFOR | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2023-12-07 | — | — | US | disclosed |
| CN-114426597-B | Preparation method of olefin polymerization catalyst component and prepared olefin polymerization catalyst component | 中国石油化工股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| EP-1666505-A1 | CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2006-06-07 | — | — | EP | disclosed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | disclosed |
| US-20050119427-A1 | Catalyst component and catalyst for olefin polymerization as well as use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-06-02 | — | — | US | disclosed |