Benzoic Acid

Benzoic Acid

SCHEMBL1783310

CCC(C)(O)CC(C)(O)CC.O=C(O)c1ccccc1.O=C(O)c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.54
DAO P14920 1/20 0.54
NAPRT Q6XQN6 1/20 0.54
CES2 O00748 3/20 0.47
CES1 P23141 3/20 0.47
SRD5A2 P31213 2/20 0.47
ALDH1A1 P00352 4/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CYP1A2 P05177 2/20 0.43
POLB P06746 2/20 0.43
PKM P14618 2/20 0.42
GAA P10253 1/20 0.42
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 1/20 0.41
CYP2C9 P11712 1/20 0.41
RAB9A P51151 1/20 0.41
TP53 P04637 1/20 0.41
RXRA P19793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL29006821 1.00 TSHR (0.54) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL4576581 0.93 TSHR (0.50) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL11228092 0.92 TSHR (0.58) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL1072571 0.91 TSHR (0.48) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL5082527 0.87 TSHR (0.52) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL28684602 0.87 TSHR (0.52) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL1785165 0.87 TSHR (0.44) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL29006846 0.84 TSHR (0.48) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL6934526 0.84 TSHR (0.64) TSHRDAONAPRTCES2CES1
Benzoic Acid SCHEMBL2032078 0.84 TSHR (0.64) TSHRDAONAPRTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290623-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290625-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-118290624-A Polypropylene and preparation method and application thereof 中国石油化工股份有限公司 2024-07-05 CN claimed
CN-117756970-A Catalyst for butene-1 polymerization and application thereof 中国石油化工股份有限公司 2024-03-26 CN claimed
CN-115975075-A Catalyst component for olefin polymerization, catalyst and application 中国石油化工股份有限公司 2023-04-18 CN claimed
CN-114478846-A Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst 中国石油化工股份有限公司 2022-05-13 CN claimed
CN-113444189-A Catalyst for olefin polymerization and application thereof 中国石油化工股份有限公司 2021-09-28 CN claimed
EP-3059264-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEM CORP (CN) 2018-12-26 EP claimed
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP claimed
US-20160264694-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-09-15 US claimed
EP-3059264-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PREPARATION METHOD THEREOF, AND CATALYST COMPRISING SAME China Petroleum&Chemical Corporation (CN) 2016-08-24 EP claimed
CN-104558282-A Catalyst component used for olefin polymerization and preparation method thereof as well as catalyst used for olefin polymerization and application CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-103665205-A Catalyst component applied to olefin polymerization, preparation method thereof, catalyst for olefin polymerization and application of catalyst CHINA PETROLEUM & CHEMICAL 2014-03-26 CN claimed
US-7388061-B2 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-06-17 US claimed
US-20050239636-A1 Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-10-27 US claimed
US-20250320318-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD CHINA PETROLEUM & CHEM CORP (CN) 2025-10-16 US disclosed
EP-4424720-A1 OLEFIN POLYMERIZATION CATALYST COMPONENT, CATALYST SYSTEM, PREPOLYMERIZATION CATALYST COMPOSITION AND OLEFIN POLYMERIZATION METHOD CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2024-09-04 EP disclosed
US-20050119427-A1 Catalyst component and catalyst for olefin polymerization as well as use thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2005-06-02 US disclosed
CN-1453298-A Catalyst for olefine polymerizing reaction and its components CHINA PETROCHEMICAL CORP (CN) 2003-11-05 CN disclosed
CN-1436237-A Nucleotide sequences involved in increasing or decreasing ovulation rate in mammals AGRES LTD (NZ) 2003-08-13 CN disclosed