Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 5/20 | 0.42 |
| ▸ | ABL1 | P00519 | 5/20 | 0.42 |
| ▸ | HCK | P08631 | 3/20 | 0.42 |
| ▸ | BLK | P51451 | 3/20 | 0.42 |
| ▸ | FRK | P42685 | 2/20 | 0.42 |
| ▸ | BTK | Q06187 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | ITK | Q08881 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23157415 | 0.97 | SRC (0.41) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL17699271 | 0.83 | SRC (0.44) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL20553297 | 0.82 | BTK (0.42) | SRCBLKBTKLCKFYN | |
| SCHEMBL17699298 | 0.81 | SRC (0.45) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL29669814 | 0.80 | PTK6 (0.43) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL19294566 | 0.80 | PTK6 (0.43) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL25030580 | 0.78 | SRC (0.59) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL16701529 | 0.78 | PTK6 (0.45) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL16701431 | 0.77 | PIK3CD (0.40) | SRCPTK6ABL1HCKBLK | |
| SCHEMBL17853712 | 0.77 | HDAC1 (0.46) | SRCBTKLCKEGFRJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695181-B2 | Hydroximic acid derivatives and medical applications therof | Feng, Zixia (CN) | 2017-07-04 | — | — | US | disclosed |
| US-9695181-B2 | Hydroximic acid derivatives and medical applications therof | Feng, Zixia (CN) | 2017-07-04 | — | — | US | disclosed |
| US-20160176879-A1 | Novel Hydroximic Acid Derivative and Medical Application Thereof | ZENG, ZIXIA (CN) | 2016-06-23 | — | — | US | disclosed |
| US-20160176879-A1 | Novel Hydroximic Acid Derivative and Medical Application Thereof | ZENG, ZIXIA (CN) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176879-A1 | Novel Hydroximic Acid Derivative and Medical Application Thereof | HCAR2, HCAR1, HDAC5 | SRC 521/4885PTK6 152/4885ABL1 724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.