Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA4 | P22748 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17847815 | 0.81 | PPARG (0.42) | MAOBPPARGRXRACA12CA4 | |
| SCHEMBL17847820 | 0.81 | PPARG (0.42) | MAOBPPARGRXRACA12CA4 | |
| SCHEMBL17847897 | 0.80 | HPGD (0.46) | MAOBPPARGALDH1A1 | |
| SCHEMBL17847896 | 0.80 | HPGD (0.46) | MAOBPPARGALDH1A1 | |
| SCHEMBL20409059 | 0.80 | RXRA (0.42) | MAOBPPARGRXRACA12CA4 | |
| SCHEMBL17853898 | 0.78 | PPARG (0.58) | MAOBPPARGRXRAALDH1A1 | |
| SCHEMBL17847722 | 0.71 | HPGD (0.43) | PPARGALDH1A1 | |
| SCHEMBL17847723 | 0.71 | HPGD (0.43) | PPARGALDH1A1 | |
| SCHEMBL21376109 | 0.70 | LCK (0.38) | PPARGRXRACA12CA4CA9 | |
| SCHEMBL22109777 | 0.69 | HPGD (0.45) | PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100546-A1 | METHOD OF TREATING OR PREVENTING RAS-MEDIATED DISEASES | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2016100542-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |