SCHEMBL17854013

SCHEMBL17854013

N[C@H]1C([C@H](O)[C@H](O)CO)O[C@@](OCC2O[C@H](OCCCCCNC(=O)CCS)C(O)[C@@H](O)[C@H]2O)(C(=O)O)C[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SIGLEC7 Q9Y286 2/20 0.48
▸ CD22 P20273 17/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17854010 0.87 SIGLEC7 (0.51) SIGLEC7CD22
SCHEMBL17897329 0.84 SIGLEC7 (0.53) SIGLEC7CD22
SCHEMBL17988604 0.81 SIGLEC7 (0.56) SIGLEC7CD22
SCHEMBL17853997 0.80 CD22 (0.41) SIGLEC7CD22
SCHEMBL17854014 0.79 SIGLEC7 (0.63) SIGLEC7CD22
SCHEMBL15473997 0.79 SIGLEC7 (0.59) SIGLEC7CD22
SCHEMBL18733276 0.78 CD22 (0.43) SIGLEC7CD22
SCHEMBL31668635 0.78 CD22 (0.43) SIGLEC7CD22
SCHEMBL18732828 0.78 CD22 (0.43) SIGLEC7CD22
SCHEMBL20193260 0.78 SIGLEC7 (0.47) SIGLEC7CD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160175421-A1 GLYCAN CONJUGATES AND USE THEREOF WONG CHI-HUEY (US) 2016-06-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160175421-A1 GLYCAN CONJUGATES AND USE THEREOF FUT5, GNE, B3GNT2 SIGLEC7 7/4885CD22 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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