Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 10/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.53 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL31563671 | 0.98 | EPHX2 (0.51) | EPHX2NR1H4LOXL2KDM4ECYP3A4 | |
| SCHEMBL20902781 | 0.83 | CA1 (0.65) | EPHX2NR1H4CA1CA2HDAC3 | |
| SCHEMBL20283130 | 0.82 | LOXL2 (0.47) | EPHX2NR1H4LOXL2KDM4ECYP3A4 | |
| SCHEMBL13247118 | 0.82 | LOXL2 (0.47) | EPHX2NR1H4LOXL2KDM4ECYP3A4 | |
| SCHEMBL14108213 | 0.82 | LOXL2 (0.47) | EPHX2NR1H4LOXL2KDM4ECYP3A4 | |
| SCHEMBL2504209 | 0.82 | KDM4E (0.68) | LOXL2KDM4ECYP3A4MAPT | |
| SCHEMBL13168316 | 0.81 | CA1 (0.53) | EPHX2NR1H4KDM4ECA1CA2 | |
| SCHEMBL25588076 | 0.81 | EPHX2 (0.49) | EPHX2NR1H4CA1CA2HDAC3 | |
| SCHEMBL9312691 | 0.80 | LOXL2 (0.45) | EPHX2NR1H4LOXL2KDM4ECYP3A4 | |
| SCHEMBL348623 | 0.79 | TSHR (0.52) | EPHX2NR1H4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493384-B | Preparation method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116813479-A | Preparation method of butenafine hydrochloride | 山东新时代药业有限公司 | 2023-09-29 | — | — | CN | claimed |
| CN-112209837-B | Synthesis method of bributin hydrochloride | 鲁南制药集团股份有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-114824092-A | Solar cell based on quasi two-dimensional-two-dimensional perovskite and preparation method thereof | 河北工业大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114420852-A | Preparation method of pure-phase RP perovskite film | 河北工业大学 | 2022-04-29 | — | — | CN | claimed |
| CN-113493384-A | Preparation method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-112209837-A | Synthesis method of butenaphthol hydrochloride | 鲁南制药集团股份有限公司 | 2021-01-12 | — | — | CN | claimed |
| JP-61000045-A | — | — | None | — | — | JP | disclosed |
| JP-9169711-A | — | — | None | — | — | JP | disclosed |
| JP-3200747-A | — | — | None | — | — | JP | disclosed |
| CN-113493388-B | Synthesis method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-113493384-B | Preparation method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113493384-B | Preparation method of butenafine hydrochloride | 鲁南制药集团股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| US-5021458-A | Amine derivatives and fungicides containing the same | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0164697-B1 | AMINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND FUNGICIDES CONTAINING THE SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4939148-A | Amine derivatives, processes for their production and their use | SANDOZ, LTD. (CH) | 1990-07-03 | — | — | US | disclosed |
| CN-1007975-B | Process for the preparation of amine derivatives | KAKEN PHARMACEUFICAL CO LTD (JP) | 1990-05-16 | — | — | CN | disclosed |
| CN-85104330-A | Process for the preparation of amine derivatives and fungicides containing amine derivatives | — | 1986-12-03 | — | — | CN | disclosed |
| JP-S6145-A | NAPHTHYLMETHYLAMINE DERIVATIVE AND ANTIFUNGAL CONTAINING THE SAME | KAKEN PHARMACEUT CO LTD | 1986-01-06 | — | — | JP | disclosed |
| EP-0164697-A2 | Amine derivatives, processes for preparing the same and fungicides containing the same | Kaken Pharmaceutical Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |