SCHEMBL17855941

SCHEMBL17855941

c1ccc(C2(c3ccccc3)c3ccccc3-c3cc(N(c4cccc5oc6ccccc6c45)c4cccc5oc6ccccc6c45)ccc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
OPRK1 P41145 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25145801 0.94 KDM4E (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL25472827 0.94 KDM4E (0.32) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL17855918 0.94 ALOX5 (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL17855925 0.93 KDM4E (0.34) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL21094687 0.93 KDM4E (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL25145673 0.93 KDM4E (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL17855936 0.93 KDM4E (0.35) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL21094593 0.93 MEN1 (0.33) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL26025365 0.93 KDM4E (0.31) MEN1KMT2AKDM4ELMNAMAPT
SCHEMBL22680229 0.92 KDM4E (0.30) MEN1KMT2AKDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160181525-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed
US-20160181525-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160181525-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT MATERIAL, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE ESR1, ESR2, CCNE2 MEN1 782/4885KMT2A 917/4885KDM4E 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.