⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900486 | 0.77 | — | — | |
| SCHEMBL12317027 | 0.64 | — | — | |
| SCHEMBL19361245 | 0.62 | — | — | |
| SCHEMBL598898 | 0.61 | ALDH1A1 (0.50) | — | |
| SCHEMBL81105 | 0.61 | — | — | |
| Methoxymethane SCHEMBL21313361 | 0.59 | ALDH1A1 (0.36) | — | |
| SCHEMBL19226305 | 0.57 | ALDH1A1 (0.44) | — | |
| SCHEMBL8055318 | 0.57 | — | — | |
| Ammonia Solution, Strong SCHEMBL5183336 | 0.57 | — | — | |
| SCHEMBL27481574 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298745-B1 | PREPARATION METHOD OF ROSUVASTATIN CALCIUM AND ITS INTERMEDIATES | CHANGZHOU PHARMACEUTICAL FACTORY (CN) | 2014-09-03 | — | — | EP | claimed |
| US-8653265-B2 | Preparation method of rosuvastatin calcium and its intermediates | CHANGZHOU PHARMACEUTICAL FACTORY (CN) | 2014-02-18 | — | — | US | disclosed |
| US-20110124864-A1 | PREPARATION METHOD OF ROSUVASTATIN CALCIUM AND ITS INTERMEDIATES | CHANGZHOU PHARMACEUTICAL FACTORY (CN) | 2011-05-26 | — | — | US | disclosed |