⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24801869 | 0.78 | — | — | |
| SCHEMBL24337595 | 0.77 | TP53 (0.35) | — | |
| SCHEMBL12717919 | 0.75 | ESR1 (0.34) | — | |
| SCHEMBL5069790 | 0.75 | GAA (0.36) | — | |
| SCHEMBL23775665 | 0.75 | KIF11 (0.32) | — | |
| SCHEMBL21772277 | 0.75 | GAA (0.36) | — | |
| SCHEMBL15366079 | 0.75 | ESR1 (0.32) | — | |
| SCHEMBL23374669 | 0.74 | PIK3CD (0.37) | — | |
| Hydrochloric Acid SCHEMBL25368246 | 0.74 | GAA (0.35) | — | |
| Hydrochloric Acid SCHEMBL25367847 | 0.74 | ESR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130203730-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2013-08-08 | — | — | US | disclosed |
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |
| US-20120115845-A1 | THERAPEUTIC AGENTS | ALLEN JACK MCQUEEN (GB) | 2012-05-10 | — | — | US | disclosed |
| US-20110124621-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | ASTRAZENECA AB (SE) | 2011-05-26 | — | — | US | disclosed |
| US-20090186870-A1 | Therapeutic Agents - 802 | ASTRAZENECA AB (SE) | 2009-07-23 | — | — | US | disclosed |