Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20677639 | 1.00 | RORC (0.61) | RORCIL17A | |
| SCHEMBL17843892 | 0.91 | RORC (0.73) | RORCIL17A | |
| SCHEMBL17843840 | 0.87 | RORC (0.76) | RORCIL17A | |
| SCHEMBL20677625 | 0.87 | RORC (0.64) | RORCIL17A | |
| SCHEMBL17859192 | 0.87 | RORC (0.64) | RORCIL17A | |
| SCHEMBL20262142 | 0.85 | RORC (0.84) | RORCIL17A | |
| SCHEMBL20684098 | 0.85 | RORC (0.84) | RORCIL17A | |
| SCHEMBL20262143 | 0.85 | RORC (0.84) | RORCIL17A | |
| SCHEMBL17860848 | 0.85 | RORC (0.84) | RORCIL17A | |
| SCHEMBL17843868 | 0.84 | RORC (0.56) | RORCIL17A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233838-B1 | BENZIMIDAZOLE SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RES & DEV (FR) | 2019-01-30 | — | — | EP | disclosed |
| WO-2016097393-A1 | BENZIMIDAZOLE SULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | disclosed |