SCHEMBL178592

SCHEMBL178592

O=C(O)C1NCC[C@@H]1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1364961 1.00
SCHEMBL1256601 1.00
SCHEMBL63812 1.00
SCHEMBL7412 1.00
SCHEMBL114870 1.00
SCHEMBL2025245 1.00
SCHEMBL8088 1.00
SCHEMBL200242 1.00
Hydrochloric Acid SCHEMBL23391535 0.98 SLC1A2 (0.58)
Methane SCHEMBL14937659 0.98 SLC1A2 (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4076492-A1 PCSK9 ANTAGONIST COMPOUNDS Merck Sharp & Dohme LLC (US) 2022-10-26 EP disclosed
WO-2018236928-A1 HEPATITIS C VIRUS NS3/4A PROTEASE INHIBITORS UNIVERSITY OF MASSACHUSETTS (US) 2018-12-27 WO disclosed
EP-3226900-A1 IDENTIFICATION OF VSIG8 AS THE PUTATIVE VISTA RECEPTOR AND ITS USE THEREOF TO PRODUCE VISTA/VSIG8 MODULATORS Immunext, Inc. (US) 2017-10-11 EP disclosed
WO-2016090347-A1 IDENTIFICATION OF VSIG8 AS THE PUTATIVE VISTA RECEPTOR AND ITS USE THEREOF TO PRODUCE VISTA/VSIG8 MODULATORS IMMUNEXT, INC. (US) 2016-06-09 WO disclosed
US-9061959-B2 Method for manufacturing optically active menthol TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-06-23 US disclosed
US-9000192-B2 Catalyst for asymmetric hydrogenation and method for manufacturing optically active carbonyl compound using the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-04-07 US disclosed
EP-2675912-A1 METHOD FOR ASSAYING OGFOD1 ACTIVITY Isis Innovation Ltd (GB) 2013-12-25 EP disclosed
EP-2647616-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL Takasago International Corporation (JP) 2013-10-09 EP disclosed
US-20130253228-A1 METHOD FOR MANUFACTURING OPTICALLY ACTIVE MENTHOL TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-09-26 US disclosed
US-20130217895-A1 CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-08-22 US disclosed
EP-1725542-A1 VLA-4 ANTAGONISTS Merck & Co., Inc. (US) 2006-11-29 EP disclosed
WO-2006115918-A2 VLA-4 ANTAGONISTS MERCK & CO., INC. (US) 2006-11-02 WO disclosed
WO-2006023396-A2 VLA-4 ANTAGONISTS MERCK & CO., INC. (US) 2006-03-02 WO disclosed
US-20050277167-A1 Prolyl 3-hydroxylases SHRINERS HOSPITALS FOR CHILDREN 2005-12-15 US disclosed
WO-2005112999-A2 CANCER TREATMENT WITH INHIBITORS OF COLLAGEN SYNTHESIS VECTRAMED, INC. (US) 2005-12-01 WO disclosed
WO-2005087760-A1 VLA-4 ANTAGONISTS MERCK & CO., INC. (US) 2005-09-22 WO disclosed
EP-1416932-A1 NEW DIPEPTIDYL PEPTIDASE IV INHIBITORS AND THEIR USES FOR LOWERING BLOOD PRESSURE LEVELS Probiodrug AG (DE) 2004-05-12 EP disclosed
WO-2003015775-A1 NEW DIPEPTIDYL PEPTIDASE IV INHIBITORS AND THEIR USES FOR LOWERING BLOOD PRESSURE LEVELS PROBIODRUG AG (DE) 2003-02-27 WO disclosed
EP-1014945-A1 CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS The Regents of the University of California (US) 2000-07-05 EP disclosed
WO-1998040052-A1 CATIONIC LIPID COMPOSITIONS TARGETING ANGIOGENIC ENDOTHELIAL CELLS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1998-09-17 WO disclosed