⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1364961 | 1.00 | — | — | |
| SCHEMBL1256601 | 1.00 | — | — | |
| SCHEMBL178592 | 1.00 | — | — | |
| SCHEMBL63812 | 1.00 | — | — | |
| SCHEMBL114870 | 1.00 | — | — | |
| SCHEMBL2025245 | 1.00 | — | — | |
| SCHEMBL8088 | 1.00 | — | — | |
| SCHEMBL200242 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL23391535 | 0.98 | SLC1A2 (0.58) | — | |
| Methane SCHEMBL14937659 | 0.98 | SLC1A2 (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3639 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120192903-A | Genetically engineered bacterium and application thereof in production of cis-3-hydroxy-L-proline | 上海合全药业股份有限公司 | 2025-06-24 | — | — | CN | claimed |
| WO-2025124444-A1 | USE OF HYDROXYPROLINE AND DERIVATIVE THEREOF, BIOLOGICAL HERBICIDE, BROAD-SPECTRUM HERBICIDE, AND WEED CONTROL METHOD | 三亚市国家耐盐碱水稻技术创新中心 | 2025-06-19 | — | — | WO | claimed |
| CN-120130489-A | Application of hydroxyproline and derivatives thereof, biological herbicide, broad-spectrum herbicide and weed control method | 三亚市国家耐盐碱水稻技术创新中心 | 2025-06-13 | — | — | CN | claimed |
| CN-116496314-B | Preparation method of (2S, 4S) -1- (tert-butyloxycarbonyl) -4- (tert-butyldimethylsilyloxy) -2-methylpyrrolidine-2-carboxylic acid | 南京优氟医药科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| US-20240382605-A1 | CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2024-11-21 | — | — | US | claimed |
| US-12121684-B1 | Method of treating normal pressure hydrocephalus | HAKIM CARLOS (US) | 2024-10-22 | — | — | US | claimed |
| CN-118510522-A | Conjugated oligonucleotides and uses thereof | IONIS制药公司 | 2024-08-16 | — | — | CN | claimed |
| EP-4408433-A1 | CONJUGATED OLIGONUCLEOTIDES AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2024-08-07 | — | — | EP | claimed |
| US-11904020-B2 | Bicyclic peptide ligands specific for TREM2 | BICYCLETX LIMITED (GB) | 2024-02-20 | — | — | US | claimed |
| EP-4308586-A1 | BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TREM2 | BicycleTX Limited (GB) | 2024-01-24 | — | — | EP | claimed |
| CN-1106458-A | Process for producing cis-3-hydroxy-L-proline | KYOWA HAKKO KOGYO KK (JP) | 1995-08-09 | — | — | CN | claimed |
| WO-1995019764-A1 | CIS-HYDROXYPROLINE ANALOGS FOR EYE TREATMENT | JAVITT JONATHAN (US) | 1995-07-27 | — | — | WO | claimed |
| EP-0645457-A2 | Process for producing cis-3-hydroxy-L-proline | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-03-29 | — | — | EP | claimed |
| US-5372807-A | Proline analogs administered to inhibit collagen accumulation | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1994-12-13 | — | — | US | claimed |
| EP-0548083-A1 | NERVE-REGENERATING AGENT | Wehling, Peter, Dr. med. (DE) | 1993-06-30 | — | — | EP | claimed |
| US-5135920-A | Administering dextran sulfate, beta-1,3-glucan sulfate or salts; steroids, fumagillins; treating vision defects, arthritis; diseases caused by abnormally accelerated angiogenesis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-08-04 | — | — | US | claimed |
| WO-1991019508-A1 | NERVE-REGENERATING AGENT | WEHLING PETER (DE) | 1991-12-26 | — | — | WO | claimed |
| US-5021404-A | Angiostatic collagen modulators | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1991-06-04 | — | — | US | claimed |
| WO-1991000119-A1 | IMPLANTABLE DEVICE | BAXTER INTERNATIONAL INC. (US) | 1991-01-10 | — | — | WO | claimed |
| EP-0307390-A2 | Chemical compound consisting of cis-3-hydroxyproline for therapeutic treatment, and process for its preparation | MERCKLE GMBH (DE) | 1989-03-15 | — | — | EP | claimed |