Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
| ▸ | POLD1 | P28340 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.33 |
| ▸ | TYMP | P19971 | 4/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.33 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.31 |
| ▸ | TK1 | P04183 | 3/20 | 0.31 |
| ▸ | POLG | P54098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17859331 | 0.83 | POLB (0.31) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL16299256 | 0.78 | POLB (0.43) | POLBPOLA1POLD1P2RY2TYMP | |
| SCHEMBL17859315 | 0.77 | POLB (0.35) | POLBPOLA1POLD1P2RY2TYMP | |
| SCHEMBL16575823 | 0.71 | P2RY2 (0.34) | POLBPOLA1POLD1P2RY2P2RY4 | |
| SCHEMBL21418844 | 0.69 | P2RY2 (0.45) | POLA1P2RY2P2RY4P2RY6ENPP1 | |
| SCHEMBL28563636 | 0.69 | POLB (0.38) | POLBPOLA1POLD1P2RY2TYMP | |
| SCHEMBL23805468 | 0.69 | TYMP (0.43) | POLBPOLA1POLD1P2RY2TYMP | |
| SCHEMBL16575819 | 0.68 | P2RY2 (0.44) | POLA1P2RY2P2RY4P2RY6ENPP1 | |
| SCHEMBL16576112 | 0.67 | POLG (0.37) | P2RY2P2RY4P2RY6ENPP1POLG | |
| SCHEMBL16575829 | 0.66 | P2RY2 (0.31) | P2RY2P2RY4P2RY6ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016099982-A2 | PHOSPHORAMIDATES FOR THE TREATMENT OF HEPATITIS B VIRUS | EMORY UNIVERSITY (US) | 2016-06-23 | — | — | WO | disclosed |