Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | POLD1 | P28340 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 4/20 | 0.36 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.35 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805468 | 0.88 | TYMP (0.43) | POLBPOLA1POLD1TYMPP2RY2 | |
| SCHEMBL18790012 | 0.82 | POLB (0.39) | POLBPOLA1POLD1TYMPP2RY2 | |
| Triphosphate SCHEMBL10475447 | 0.79 | TYMP (0.43) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL17859319 | 0.78 | POLB (0.39) | POLBPOLA1POLD1TYMPP2RY2 | |
| SCHEMBL24895801 | 0.73 | POLB (0.37) | POLBPOLA1POLD1TYMPP2RY2 | |
| SCHEMBL15676676 | 0.73 | TK1 (0.43) | POLBPOLA1POLD1TYMPTK1 | |
| SCHEMBL16038197 | 0.72 | TYMP (0.60) | TYMPTK1 | |
| SCHEMBL18290459 | 0.71 | P2RY6 (0.35) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL15948684 | 0.70 | TYMP (0.42) | POLBTYMPTK1 | |
| Triphosphate SCHEMBL10475441 | 0.70 | TYMP (0.46) | POLBPOLA1POLD1TYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027625-A2 | SCAFFOLD-BASED POLYMERASE ENZYME SUBSTRATES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | WO | disclosed |