Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LYPLA1 | O75608 | 1/20 | 0.37 |
| ▸ | LYPLA2 | O95372 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16782015 | 0.91 | TSHR (0.50) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL16782014 | 0.91 | TSHR (0.50) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL16782139 | 0.91 | TSHR (0.50) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL6868253 | 0.77 | ALDH1A1 (0.44) | TDP1ALDH1A1IDO1SMN1; SMN2 | |
| SCHEMBL2640223 | 0.77 | TSHR (0.70) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL8621469 | 0.77 | TSHR (0.70) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL1991359 | 0.76 | TSHR (0.78) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011715 | 0.74 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011624 | 0.74 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 | |
| SCHEMBL9011734 | 0.74 | TSHR (0.67) | TSHRL3MBTL1TDP1NAAAHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016098054-A1 | PROCESSES FOR PREPARING OXATHIAZIN-LIKE COMPOUNDS | GEISTLICH PHARMA AG (CH) | 2016-06-23 | — | — | WO | disclosed |