Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 5/20 | 0.71 |
| ▸ | CDK2 | P24941 | 5/20 | 0.71 |
| ▸ | CDK1 | P06493 | 3/20 | 0.71 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.50 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767031 | 0.83 | CCNE1 (1.00) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL22348820 | 0.82 | CCNE1 (0.52) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL19829082 | 0.81 | CCNE1 (0.73) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL14569467 | 0.81 | CCNE1 (0.48) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL27854926 | 0.80 | CDK1 (0.71) | CCNE1CDK2CDK1CCNB1HSP90AA1 | |
| SCHEMBL14595245 | 0.80 | ADORA2A (0.56) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL20577001 | 0.80 | CCNE1 (0.45) | CCNE1CDK2CDK1CCNB1CYP2C19 | |
| SCHEMBL27576997 | 0.80 | CCNE1 (0.45) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| Penciclovir SCHEMBL29357169 | 0.79 | CCNE1 (0.46) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| Penciclovir SCHEMBL19236307 | 0.79 | CCNE1 (0.46) | CCNE1CDK2CDK1CCNB1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096174-A1 | FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | INVIVOGEN (FR) | 2016-06-23 | — | — | WO | disclosed |