Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 4/20 | 0.73 |
| ▸ | CDK2 | P24941 | 4/20 | 0.73 |
| ▸ | CDK1 | P06493 | 3/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.73 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767031 | 0.84 | CCNE1 (1.00) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL28221531 | 0.82 | ADORA2A (0.53) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL17860490 | 0.81 | CCNE1 (0.71) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL27854926 | 0.81 | CDK1 (0.71) | CCNE1CDK2CDK1CCNB1HSP90AB1 | |
| SCHEMBL27320701 | 0.81 | CCNE1 (0.51) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL12193833 | 0.79 | CCNE1 (0.48) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL14611764 | 0.79 | CDK1 (0.48) | CCNE1CDK2CDK1CCNB1HSP90AB1 | |
| SCHEMBL17364319 | 0.79 | CDK1 (0.67) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL18521191 | 0.79 | CCNE1 (0.67) | CCNE1CDK2CDK1CCNB1ADORA2A | |
| SCHEMBL26036734 | 0.79 | CDK1 (0.67) | CCNE1CDK2CDK1CCNB1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180029905-A1 | THERMORESPONSIVE POLYMERS FOR AQUEOUS APPLICATIONS | PHILLIPS 66 COMPANY (US) | 2018-02-01 | — | — | US | disclosed |