SCHEMBL178607

SCHEMBL178607

OC(=S)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.45
TSHR P16473 1/20 0.45
TDP1 Q9NUW8 2/20 0.43
ATM Q13315 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CA5A P35218 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CA4 P22748 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAPT P10636 2/20 0.41
NR1H2 P55055 1/20 0.40
BAX Q07812 1/20 0.40
RAB9A P51151 1/20 0.39
RAD51 Q06609 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10789411 0.97 LTA4H (0.43) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL2470101 0.82 LTA4H (0.45) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL3087192 0.82 LTA4H (0.45) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL11171421 0.80 LTA4H (0.43) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL3076764 0.79 LTA4H (0.38) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL1276245 0.78 LTA4H (0.41) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL7346936 0.78 LTA4H (0.41) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL2784281 0.78 TSHR (0.41) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL761789 0.78 CA4 (0.43) LTA4HTSHRTDP1ATML3MBTL1
SCHEMBL3038674 0.78 TSHR (0.41) LTA4HTSHRTDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486771-A Thiocarbonate-based hydrogen sulfide donor, and preparation method and application thereof 上海交通大学 2024-02-02 CN claimed
CN-115850356-A Deoxynucleoside analogue and preparation method thereof 华东理工大学 2023-03-28 CN claimed
CN-115745899-A Mercury (II) fluorescent probe, preparation method and application thereof 郑州师范学院 2023-03-07 CN claimed
CN-113292535-B Method for preparing apaluamide intermediate and apaluamide 南京方生和医药科技有限公司 2022-07-01 CN claimed
CN-114040778-A Cell binding molecule-Tubulysin derivative conjugate and preparation method thereof 杭州多禧生物科技有限公司 2022-02-11 CN claimed
CN-113292535-A Method for preparing apaluamide intermediate and apaluamide 南京方生和医药科技有限公司 2021-08-24 CN claimed
CN-112961087-A Preparation process of high-yield phenyl isothiocyanate derivative 刘科技 2021-06-15 CN claimed
CN-112939833-A High-yield production process of phenyl isothiocyanate derivative 刘科技 2021-06-11 CN claimed
CN-111057047-B Near-infrared fluorescent probe for detecting Cys in brain of depression mouse and synthetic method and application thereof 山东师范大学 2021-02-23 CN claimed
CN-110698322-B Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2021-01-26 CN claimed
EP-0778843-A1 INTERMEDIATES FOR DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES Novartis AG (CH) 1997-06-18 EP claimed
US-5508270-A Nucleoside phosphinate compounds and compositions CIBA-GEIGY CORPORATION (US) 1996-04-16 US claimed
WO-1996008503-A1 INTERMEDIATES FOR DINUCLEOTIDE AND OLIGONUCLEOTIDE ANALOGUES NOVARTIS AG (CH) 1996-03-21 WO claimed
WO-1996007666-A1 MONONUCLEOTIDE AND DINUCLEOTIDE ANALOGUES AND INTERMEDIATES THEREFOR NOVARTIS AG (CH) 1996-03-14 WO claimed
US-5466677-A Dinucleoside phosphinates and their pharmaceutical compositions CIBA-GEIGY CORPORATION (US) 1995-11-14 US claimed
EP-0629633-A2 Dinucleotide analogues, intermediates therefor and oligonucleotides derived therefrom CIBA-GEIGY AG (CH) 1994-12-21 EP claimed
EP-0614906-A1 Mononucleotide analogues and intermediates therefor CIBA-GEIGY AG (CH) 1994-09-14 EP claimed
EP-0614907-A1 Dinucleotide and oligonucleotide analogues CIBA-GEIGY AG (CH) 1994-09-14 EP claimed
US-5241084-A PREPARATION PROCESS OF GINKGOLIDE B FROM GINKGOLIDE C SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 1993-08-31 US claimed
EP-0229034-A2 Hexopyranoses and compositions for agricultural use HER MAJESTY THE QUEEN in right of New Zealand Department of Scientific and Industrial Research (NZ) 1987-07-15 EP claimed