Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12251777 | 0.79 | LMNA (0.46) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL17882175 | 0.77 | LMNA (0.43) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL19759288 | 0.77 | LMNA (0.43) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL15423495 | 0.75 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL13684775 | 0.75 | LMNA (0.42) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL17860952 | 0.75 | — | — | |
| SCHEMBL18848909 | 0.73 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL10082814 | 0.73 | MEN1 (0.42) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL19447747 | 0.73 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15KMT2A | |
| SCHEMBL19447757 | 0.73 | LMNA (0.40) | LMNAMEN1CYP3A4ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100578-A2 | ANTIMICROBIAL POLYMYXINS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |