Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3 | P56703 | 2/20 | 0.44 |
| ▸ | SFRP1 | Q8N474 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | RHOC | P08134 | 1/20 | 0.39 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860940 | 0.97 | HSD17B10 (0.47) | WNT3SFRP1HSD17B10KCNH2MCHR1 | |
| SCHEMBL17860757 | 0.97 | HSD17B10 (0.47) | WNT3SFRP1HSD17B10KCNH2MCHR1 | |
| SCHEMBL4274713 | 0.93 | HSD17B10 (0.48) | WNT3SFRP1HSD17B10KCNH2MCHR1 | |
| SCHEMBL4272965 | 0.91 | HSD17B10 (0.52) | WNT3SFRP1HSD17B10STSMEN1 | |
| SCHEMBL4276665 | 0.91 | HSD17B10 (0.52) | WNT3SFRP1HSD17B10STSMEN1 | |
| SCHEMBL4272968 | 0.91 | HSD17B10 (0.52) | WNT3SFRP1HSD17B10STSMEN1 | |
| SCHEMBL8374022 | 0.87 | CYP1A2 (0.40) | WNT3SFRP1STSEPHX2GLS | |
| SCHEMBL4276575 | 0.80 | CYP1A2 (0.43) | STSEPHX2RHOCRHOAGLS | |
| SCHEMBL4276573 | 0.80 | CYP1A2 (0.43) | STSEPHX2RHOCRHOAGLS | |
| SCHEMBL6863335 | 0.79 | STS (0.56) | STSEPHX2GLSTACR1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175315-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | NEUROMED PHARMACEUTICALS, LTD. (CA) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175315-A1 | N-PIPERIDINYL ACETAMIDE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | CACNA1G, CACNA1H, CACNA1B | WNT3 4764/4885SFRP1 4856/4885HSD17B10 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.