Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 13/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.34 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17033299 | 0.82 | CCR1 (0.43) | GRM2HCRTR1HCRTR2 | |
| SCHEMBL17031855 | 0.78 | HCRTR1 (0.43) | GRM2HCRTR1HCRTR2EGLN2 | |
| SCHEMBL20336407 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL19564475 | 0.72 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL19564478 | 0.72 | HCRTR1 (0.60) | HCRTR1HCRTR2 | |
| SCHEMBL12654044 | 0.70 | HRH4 (0.47) | — | |
| SCHEMBL12654054 | 0.70 | HRH4 (0.51) | — | |
| SCHEMBL20197188 | 0.68 | HRH4 (0.54) | — | |
| SCHEMBL17001733 | 0.66 | KIT (0.41) | — | |
| SCHEMBL6236175 | 0.65 | EGLN2 (0.51) | EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015130830-A9 | CARBAMATE, ESTER, AND KETONE COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2016-06-23 | — | — | WO | disclosed |