Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4919308 | 0.85 | — | — | |
| SCHEMBL186104 | 0.84 | ADRB2 (0.40) | SMYD3KDM4EHTTEPHX1OPRK1 | |
| Hydrochloric Acid SCHEMBL2656164 | 0.83 | — | — | |
| SCHEMBL31440874 | 0.83 | KDM4E (0.42) | EPHX2SMYD3KDM4EHTTMETAP1 | |
| SCHEMBL1241470 | 0.81 | SMYD3 (0.40) | EPHX2SMYD3HTTMETAP1 | |
| SCHEMBL24972574 | 0.79 | HTT (0.31) | HTT | |
| SCHEMBL26313845 | 0.79 | HTT (0.31) | HTT | |
| SCHEMBL25769714 | 0.79 | HTT (0.31) | HTT | |
| SCHEMBL12599372 | 0.78 | KCNH2 (0.43) | EPHX2SMYD3HTT | |
| SCHEMBL19406793 | 0.76 | HTT (0.36) | EPHX2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016097389-A1 | BENZENESULFONAMIDE DERIVATIVES AS INVERSE AGONISTS OF RETINOID-RELATED ORPHAN RECEPTOR GAMMA (ROR GAMMA (T)) | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2016-06-23 | — | — | WO | disclosed |