Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 18/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17819338 | 0.96 | ELANE (0.54) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL17819331 | 0.96 | ELANE (0.54) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL17819310 | 0.96 | ELANE (0.54) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL17819351 | 0.96 | ELANE (0.58) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL17819344 | 0.94 | ELANE (0.57) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL17819348 | 0.94 | ELANE (0.57) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL21859873 | 0.94 | ELANE (0.56) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL19502788 | 0.93 | ELANE (0.55) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL21835826 | 0.92 | ELANE (0.54) | ELANEMEN1KMT2ACYP2C9CYP3A4 | |
| SCHEMBL21860404 | 0.92 | ELANE (0.54) | ELANEMEN1KMT2APDE4BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233833-B1 | NOVEL COMPOUNDS | CHIESI FARM SPA (IT) | 2019-02-20 | — | — | EP | disclosed |
| US-9409870-B2 | Compounds | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-08-09 | — | — | US | disclosed |
| US-9409870-B2 | Compounds | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-08-09 | — | — | US | disclosed |
| WO-2016096638-A1 | NOVEL COMPOUNDS | CHIESI FARMACEUTICI S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |