Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17861668 | 0.89 | DRD2 (0.69) | DRD2LTA4H | |
| SCHEMBL17861530 | 0.88 | DRD2 (0.60) | DRD2LTA4H | |
| SCHEMBL17861532 | 0.85 | DRD2 (0.60) | DRD2LTA4H | |
| SCHEMBL17861615 | 0.85 | DRD2 (0.57) | DRD2LTA4H | |
| SCHEMBL17848581 | 0.84 | DRD2 (0.74) | DRD2LTA4H | |
| SCHEMBL17861552 | 0.84 | DRD2 (0.70) | DRD2 | |
| SCHEMBL17848341 | 0.83 | DRD2 (0.72) | DRD2LTA4H | |
| SCHEMBL17848374 | 0.82 | DRD2 (0.78) | DRD2LTA4H | |
| SCHEMBL17848556 | 0.82 | DRD2 (0.85) | DRD2LTA4H | |
| SCHEMBL17848322 | 0.82 | DRD2 (0.69) | DRD2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016100940-A1 | DOPAMINE D2 RECEPTOR LIGANDS | THE BROAD INSTITUTE, INC. (US) | 2016-06-23 | — | — | WO | disclosed |