Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP1A1 | P05023 | 12/20 | 0.84 |
| ▸ | ATP1B1 | P05026 | 12/20 | 0.84 |
| ▸ | ATP1A3 | P13637 | 12/20 | 0.84 |
| ▸ | ATP1B2 | P14415 | 12/20 | 0.84 |
| ▸ | ATP1A2 | P50993 | 12/20 | 0.84 |
| ▸ | ATP1B3 | P54709 | 12/20 | 0.84 |
| ▸ | FXYD2 | P54710 | 12/20 | 0.84 |
| ▸ | ATP1A4 | Q13733 | 12/20 | 0.84 |
| ▸ | TP53 | P04637 | 5/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.81 |
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | NPC1 | O15118 | 3/20 | 0.81 |
| ▸ | RAB9A | P51151 | 3/20 | 0.81 |
| ▸ | STAT3 | P40763 | 2/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | SLCO4C1 | Q6ZQN7 | 1/20 | 0.81 |
| ▸ | HBB | P68871 | 1/20 | 0.72 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ramnodigin SCHEMBL1812161 | 1.00 | ATP1A1 (0.84) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL13475189 | 0.96 | ATP1A1 (0.88) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL14772029 | 0.94 | ATP1A1 (0.83) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17861996 | 0.93 | ATP1A1 (0.81) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17862030 | 0.92 | TP53 (0.82) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17862039 | 0.92 | TP53 (0.82) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| SCHEMBL17863988 | 0.92 | TP53 (0.82) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Digitoxigenin Monodigitoxoside SCHEMBL13897300 | 0.92 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Digitoxigenin Monodigitoxoside SCHEMBL13092978 | 0.92 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 | |
| Digitoxigenin Monodigitoxoside SCHEMBL31275966 | 0.92 | ATP1A1 (1.00) | ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160176914-A1 | GLYCOSYLATED CARDIOTONIC STEROIDS | NATIONAL INSTITUTES OF HEALTH-DIRECTOR DEITR NIH | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160176914-A1 | GLYCOSYLATED CARDIOTONIC STEROIDS | NR3C2, NR5A1, CYP11B1 | ATP1A1 1305/4885ATP1B1 1114/4885ATP1A3 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.