SCHEMBL17864097

SCHEMBL17864097

c1ccc2c(-c3nc(-n4c5ccccc5c5c6ccc7c8ccccc8ccc7c6ccc54)nc4ccccc34)cccc2c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 5/20 0.35
KDM4E B2RXH2 2/20 0.35
CYP1A2 P05177 2/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
HPRT1 P00492 1/20 0.33
FLT3 P36888 2/20 0.33
BMX P51813 1/20 0.33
ADORA2A P29274 3/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
THRB P10828 1/20 0.32
HSD17B10 Q99714 1/20 0.32
GSR P00390 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TUBB4A P04350 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22211997 0.94 ALDH1A1 (0.34) ALDH1A1HPGDKDM4ECYP1A2MAPT
SCHEMBL24104968 0.94 ALDH1A1 (0.37) ALDH1A1HPGDKDM4ECYP1A2MAPT
SCHEMBL20152152 0.91 ALDH1A1 (0.38) TDP1ALDH1A1HPGDKDM4ECYP1A2
SCHEMBL17864098 0.91 ALDH1A1 (0.40) TDP1ALDH1A1HPGDKDM4ECYP1A2
SCHEMBL19654014 0.88 GSR (0.38) ALDH1A1HPGDKDM4ECYP1A2MAPT
SCHEMBL17864091 0.88 ALDH1A1 (0.48) TDP1ALDH1A1HPGDKDM4EMAPT
SCHEMBL23471980 0.88 FLT3 (0.32) ALDH1A1HPGDKDM4EMAPTNPSR1
SCHEMBL17286933 0.87 ALDH1A1 (0.39) TDP1ALDH1A1HPGDKDM4ECYP1A2
SCHEMBL22211995 0.87 CYP1A2 (0.34) TDP1ALDH1A1HPGDKDM4ECYP1A2
SCHEMBL23471982 0.87 KDM4E (0.32) ALDH1A1HPGDKDM4EMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016099037-A2 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2016-06-23 WO disclosed