Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HAT1 | O14929 | 2/20 | 0.39 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 2/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.30 |
| ▸ | RECQL | P46063 | 2/20 | 0.30 |
| ▸ | CASP7 | P55210 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16417863 | 0.80 | HAT1 (0.50) | HDAC6HAT1RBBP7DCTPP1CCNT1 | |
| SCHEMBL12747297 | 0.76 | HDAC6 (0.50) | HDAC6CCNT1CDK9GLP1RMAPT | |
| SCHEMBL12827141 | 0.70 | HDAC6 (0.50) | HDAC6CCNT1CDK9GLP1RMAPT | |
| SCHEMBL8545269 | 0.64 | HDAC6 (0.58) | HDAC6CCNT1CDK9 | |
| SCHEMBL20132837 | 0.62 | GAA (0.49) | HDAC6MAPTALDH1A1KMT2AHSD17B10 | |
| Maribavir SCHEMBL13641208 | 0.62 | HDAC6 (1.00) | HDAC6MAPTKDM4ELMNACYP1A2 | |
| Maribavir SCHEMBL13641083 | 0.62 | HDAC6 (1.00) | HDAC6MAPTKDM4ELMNACYP1A2 | |
| SCHEMBL18459194 | 0.62 | HDAC6 (0.70) | HDAC6CCNT1CDK9MAPTKDM4E | |
| Maribavir SCHEMBL13058157 | 0.62 | HDAC6 (1.00) | HDAC6MAPTKDM4ELMNACYP1A2 | |
| SCHEMBL8796597 | 0.62 | HDAC6 (0.61) | HDAC6CCNT1CDK9GLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175338-A1 | MARIBAVIR ISOMERS, COMPOSITIONS, METHODS OF MAKING AND METHODS OF USING | VIROPHARMA INCORPORATED | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175338-A1 | MARIBAVIR ISOMERS, COMPOSITIONS, METHODS OF MAKING AND METHODS OF USING | POLB, CYP4B1, CYP3A4 | HDAC6 2079/4885HAT1 2016/4885RBBP7 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.