Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 15/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592486 | 1.00 | HDAC6 (0.58) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL7612898 | 0.93 | HDAC6 (0.54) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL7611703 | 0.93 | HDAC6 (0.54) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL7611707 | 0.93 | HDAC6 (0.54) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL8590155 | 0.83 | CCNT1 (0.43) | HDAC6CCNT1CDK9 | |
| SCHEMBL13641116 | 0.81 | HDAC6 (0.67) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL16417898 | 0.81 | HDAC6 (0.67) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL6947829 | 0.81 | HDAC6 (0.67) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL13640289 | 0.81 | HDAC6 (0.67) | HDAC6CCNT1CDK9TRPV4 | |
| SCHEMBL16417896 | 0.81 | HDAC6 (0.67) | HDAC6CCNT1CDK9TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0886635-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1998-12-30 | — | — | EP | disclosed |
| WO-1997025316-A1 | 2-AMINO-5,6-DICHLOROBENZIMIDAZOLE DERIVATIVES HAVING ANTIVIRAL ACTIVITY | GLAXO GROUP LIMITED (GB) | 1997-07-17 | — | — | WO | disclosed |