Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | GPR6 | P46095 | 6/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865138 | 1.00 | MALT1 (0.41) | MALT1GPR6HDAC3HDAC1HDAC6 | |
| SCHEMBL17847580 | 0.87 | DPP4 (0.39) | MALT1GPR6HDAC3HDAC1HDAC6 | |
| SCHEMBL17847551 | 0.87 | DPP4 (0.39) | MALT1GPR6HDAC3HDAC1HDAC6 | |
| SCHEMBL17847552 | 0.87 | DPP4 (0.39) | MALT1GPR6HDAC3HDAC1HDAC6 | |
| SCHEMBL17847554 | 0.80 | PDE10A (0.39) | — | |
| SCHEMBL17865135 | 0.80 | PDE10A (0.42) | — | |
| SCHEMBL17847595 | 0.80 | PDE10A (0.42) | — | |
| SCHEMBL17847598 | 0.80 | PDE10A (0.42) | — | |
| SCHEMBL17847535 | 0.78 | PDE10A (0.36) | GPR6HDAC3HDAC1HDAC6 | |
| SCHEMBL17847536 | 0.78 | PDE10A (0.36) | GPR6HDAC3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10369130-B2 | Antibacterial compounds | AZIEN DE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. (IT) | 2019-08-06 | — | — | US | disclosed |
| US-20170368017-A1 | ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-28 | — | — | US | disclosed |
| WO-2016096631-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10369130-B2 | Antibacterial compounds | MRPL21, CLPP, NRDC | MALT1 4718/4885GPR6 3886/4885HDAC3 979/4885 |
| US-20170368017-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, CLPP, NRDC | MALT1 4718/4885GPR6 3886/4885HDAC3 979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.