Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865136 | 1.00 | PDE10A (0.38) | PDE10AHTTHRH4HTR2CCHRM4 | |
| SCHEMBL17865135 | 0.89 | PDE10A (0.42) | PDE10AHTTHRH4HTR2C | |
| SCHEMBL17847595 | 0.89 | PDE10A (0.42) | PDE10AHTTHRH4HTR2C | |
| SCHEMBL17847598 | 0.89 | PDE10A (0.42) | PDE10AHTTHRH4HTR2C | |
| SCHEMBL17847535 | 0.82 | PDE10A (0.36) | PDE10A | |
| SCHEMBL17847536 | 0.82 | PDE10A (0.36) | PDE10A | |
| SCHEMBL17847554 | 0.82 | PDE10A (0.39) | PDE10AHRH4HTR2CCHRM4 | |
| SCHEMBL17847564 | 0.81 | HTR6 (0.37) | PDE10ACHRM4 | |
| SCHEMBL17847566 | 0.81 | HTR6 (0.37) | PDE10ACHRM4 | |
| SCHEMBL17847580 | 0.81 | DPP4 (0.39) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016096631-A1 | NEW ANTIBACTERIAL COMPOUNDS | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2016-06-23 | — | — | WO | disclosed |