SCHEMBL17865705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17865656	0.85	KMT2A (0.37)	KMT2ANPC1RAB9AALDH1A1MEN1
	SCHEMBL17865500	0.76	HRH4 (0.51)	KMT2ANPC1RAB9ASMN1; SMN2MEN1
	SCHEMBL17865640	0.72	NPC1 (0.34)	KMT2ANPC1RAB9AALDH1A1HSD17B10
	SCHEMBL22476780	0.70	HRH4 (0.51)	KMT2ANPC1RAB9AMEN1CDK2
	SCHEMBL3415446	0.70	NPY5R (0.40)	KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1
	SCHEMBL3030293	0.69	NPY5R (0.34)	KDM4EKMT2AALDH1A1HPGDHSD17B10
	SCHEMBL3030297	0.69	NPY5R (0.34)	KDM4EKMT2AALDH1A1HPGDHSD17B10
	SCHEMBL1278137	0.69	NPY5R (0.33)	CSF1R
	SCHEMBL3418132	0.69	NPY5R (0.34)	KDM4EKMT2AALDH1A1HPGDHSD17B10
	SCHEMBL1278133	0.69	NPY5R (0.33)	CSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.