Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14122934 | 0.97 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL6928063 | 0.93 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL72841 | 0.92 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3504198 | 0.91 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL25812321 | 0.90 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL3417371 | 0.89 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL16115101 | 0.88 | TSHR (0.54) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4753649 | 0.88 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL11740820 | 0.88 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8026797 | 0.88 | TSHR (0.57) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617432-B2 | Primer composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20160185975-A1 | Primer Composition | THE YOKOHAMA RUBBER CO., LTD. (JP) | 2016-06-30 | — | — | US | disclosed |
| CN-105452394-A | Primer composition | YOKOHAMA RUBBER CO LTD | 2016-03-30 | — | — | CN | disclosed |