SCHEMBL17866987

SCHEMBL17866987

CCC(C)c1cnc(C(C)C)cn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.33
ESR2 Q92731 5/20 0.33
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6468190 0.93 ESR1 (0.36) ESR1ESR2TSHR
SCHEMBL14669294 0.82 NOS3 (0.35) ESR1ESR2
SCHEMBL13104802 0.82 ESR1 (0.32) ESR1ESR2
SCHEMBL10075871 0.82 ESR1 (0.32) ESR1ESR2
SCHEMBL13841338 0.82 ESR1 (0.32) ESR1ESR2
SCHEMBL10115678 0.82 ESR1 (0.32) ESR1ESR2
SCHEMBL5950443 0.82 NOS3 (0.33) ESR1ESR2
SCHEMBL19250250 0.80 ESR1 (0.31) ESR1ESR2
SCHEMBL18202440 0.80 ESR1 (0.31) ESR1ESR2
SCHEMBL21771558 0.77 ESR1 (0.33) ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed