SCHEMBL17867012

SCHEMBL17867012

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nearest known ligand 0.74

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
XIAP P98170 1/20 0.74
POLB P06746 1/20 0.52
DPP4 P27487 12/20 0.47
DPP7 Q9UHL4 7/20 0.47
FAP Q12884 5/20 0.47
DPP8 Q6V1X1 5/20 0.47
DPP9 Q86TI2 4/20 0.47
PREP P48147 2/20 0.45
PITRM1 Q5JRX3 1/20 0.45
GRB2 P62993 1/20 0.45
LNPEP Q9UIQ6 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867011 1.00 XIAP (0.74) XIAPPOLBDPP4DPP7FAP
Diprotin A SCHEMBL6404766 0.94 XIAP (0.72) XIAPPOLBDPP4DPP7FAP
Diprotin A SCHEMBL17867000 0.94 XIAP (0.72) XIAPPOLBDPP4DPP7FAP
SCHEMBL29433188 0.91 XIAP (0.67) XIAPPOLBDPP4DPP7FAP
SCHEMBL31256939 0.91 XIAP (0.62) XIAPPOLBDPP4DPP7FAP
SCHEMBL30052704 0.91 XIAP (0.77) XIAPPOLBDPP4DPP7FAP
SCHEMBL29641757 0.89 XIAP (0.58) XIAPDPP4DPP7FAPDPP8
SCHEMBL31257009 0.89 XIAP (0.60) XIAPGRB2
SCHEMBL31257087 0.88 XIAP (0.59) XIAPPOLBGRB2LNPEP
SCHEMBL30069149 0.87 XIAP (0.63) XIAPPOLBDPP4DPP7FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622975-B2 Peptide-conjugated prodrugs BRANDEIS UNIVERSITY (US) 2026-05-12 US disclosed
CN-116283702-B Compound with antidiabetic activity and preparation method and application thereof 西南医科大学 2025-06-03 CN disclosed
CN-120058836-A Compound with antidiabetic activity and application thereof 西南医科大学 2025-05-30 CN disclosed
CN-116283702-A Compound with antidiabetic activity and preparation method and application thereof 西南医科大学 2023-06-23 CN disclosed
US-20230151057-A1 LACTIC ACID BACTERIA GROWTH PROMOTER ASAHI GROUP HOLDINGS, LTD. (JP) 2023-05-18 US disclosed
CN-114213504-B Compound with antidiabetic activity and application thereof 西南医科大学 2023-05-09 CN disclosed
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-12-08 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-114213504-A Compound with anti-diabetic activity and application thereof 西南医科大学 2022-03-22 CN disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622975-B2 Peptide-conjugated prodrugs PEPD, PAM, VIP XIAP 4043/4885POLB 1787/4885DPP4 43/4885
US-20220387610-A1 PEPTIDE-CONJUGATED PRODRUGS VIP, DNPEP, PEPD XIAP 2121/4885POLB 2157/4885DPP4 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.