SCHEMBL17867083

SCHEMBL17867083

N[C@@H]1C(O)O[C@H](C(=O)O)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@@H]1O

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 1/20 0.51
▸ MEN1 O00255 2/20 0.48
▸ KMT2A Q03164 2/20 0.48
▸ GJB2 P29033 2/20 0.48
▸ GJA1 P17302 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ TSHR P16473 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.48
▸ IGF2R P11717 2/20 0.47
▸ MAPT P10636 1/20 0.46
▸ LMNA P02545 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.42
▸ POLB P06746 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ ALOX15 P16050 1/20 0.42
▸ LGALS8 O00214 1/20 0.41
▸ LGALS3 P17931 1/20 0.41
▸ LGALS4 P56470 1/20 0.41
▸ PTPN1 P18031 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032274 0.86 FGF1 (0.52) FGF1MEN1KMT2AIGF2RLGALS8
SCHEMBL29598257 0.85 FGF1 (0.54) FGF1MEN1KMT2AGJB2GJA1
SCHEMBL10103833 0.84 CD69 (0.53) FGF1ALDH1A1SMN1; SMN2LGALS8LGALS3
SCHEMBL18122156 0.83 IGF2R (0.48) FGF1MEN1KMT2AGJB2GJA1
SCHEMBL16356748 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9
SCHEMBL8527443 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9
SCHEMBL15344535 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9
SCHEMBL13522006 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9
SCHEMBL10136157 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9
SCHEMBL15942741 0.83 MEN1 (0.54) MEN1KMT2AGJB2GJA1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 — — US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 — — US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 — — US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 — — US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 — — US disclosed
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