Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | GHSR | Q92847 | 5/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864427 | 1.00 | GAA (0.51) | GAAHTTPAX8GHSRSOAT2 | |
| SCHEMBL3124456 | 1.00 | GAA (0.51) | GAAHTTPAX8GHSRSOAT2 | |
| SCHEMBL6986236 | 0.91 | HDAC3 (0.50) | HDAC8 | |
| SCHEMBL30174305 | 0.91 | HDAC3 (0.50) | HDAC8 | |
| SCHEMBL6989670 | 0.91 | HDAC3 (0.50) | HDAC8 | |
| SCHEMBL29601883 | 0.91 | HDAC3 (0.50) | HDAC8 | |
| SCHEMBL29601701 | 0.91 | HDAC3 (0.50) | HDAC8 | |
| Zygosporamide SCHEMBL30789036 | 0.86 | SOAT2 (0.51) | GAAHTTPAX8GHSRSOAT2 | |
| SCHEMBL13399577 | 0.85 | HDAC8 (0.56) | GAAHDAC8PLA2G10PLA2G5 | |
| SCHEMBL10283637 | 0.85 | HDAC8 (0.56) | GAAHDAC8PLA2G10PLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |