SCHEMBL17867160

SCHEMBL17867160

CSCCC(N)C(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.52
MME P08473 3/20 0.45
ALDH1A1 P00352 2/20 0.43
LAP3 P28838 3/20 0.42
LMNA P02545 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FNTA P49354 3/20 0.40
FNTB P49356 3/20 0.40
PGGT1B P53609 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867157 1.00 FOLH1 (0.52) FOLH1MMEALDH1A1LAP3LMNA
SCHEMBL30051536 0.93 FOLH1 (0.56) FOLH1ALDH1A1LAP3LMNAMEN1
SCHEMBL9622054 0.93 FOLH1 (0.58) FOLH1ALDH1A1LAP3LMNAMEN1
SCHEMBL13093342 0.93 FOLH1 (0.58) FOLH1ALDH1A1LAP3LMNAMEN1
SCHEMBL9622056 0.93 FOLH1 (0.58) FOLH1ALDH1A1LAP3LMNAMEN1
SCHEMBL30052695 0.92 FOLH1 (0.55) FOLH1ALDH1A1LAP3LMNAMEN1
SCHEMBL29630632 0.90 LMNA (0.46) MMELMNAFNTAFNTBPGGT1B
SCHEMBL8012885 0.89 FOLH1 (0.55) FOLH1LMNAFNTAFNTBPGGT1B
SCHEMBL30051573 0.89 FOLH1 (0.55) FOLH1LMNAFNTAFNTBPGGT1B
SCHEMBL8012892 0.89 FOLH1 (0.55) FOLH1LMNAFNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed