SCHEMBL17867221

SCHEMBL17867221

O=C[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)[C@H]1O)[C@H](O)CO

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
FGF1 P05230 1/20 0.38
FGF2 P09038 1/20 0.38
VEGFA P15692 1/20 0.38
HPSE Q9Y251 1/20 0.38
CD209 Q9NNX6 2/20 0.38
LGALS8 O00214 1/20 0.37
LGALS3 P17931 1/20 0.37
LGALS4 P56470 1/20 0.37
SELE P16581 1/20 0.37
PTPN1 P18031 1/20 0.36
GJA1 P17302 1/20 0.36
GJB2 P29033 1/20 0.36
CYP2C9 P11712 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 1/20 0.36
IGF2R P11717 1/20 0.36
TYR P14679 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31460959 1.00 MEN1 (0.39) MEN1KMT2AFGF1FGF2VEGFA
SCHEMBL17866964 1.00 MEN1 (0.39) MEN1KMT2AFGF1FGF2VEGFA
SCHEMBL22498757 0.94 MEN1 (0.40) MEN1KMT2AFGF1FGF2VEGFA
SCHEMBL22498755 0.94 MEN1 (0.40) MEN1KMT2AFGF1FGF2VEGFA
SCHEMBL14936496 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
SCHEMBL15373700 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
SCHEMBL14936334 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
SCHEMBL12362685 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
SCHEMBL17223127 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4
Cellohexose SCHEMBL14796364 0.93 LGALS8 (0.44) MEN1KMT2ALGALS8LGALS3LGALS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed