SCHEMBL17867228

SCHEMBL17867228

C/C1=C\CC(O)[C@H](C)/C=C/[C@H](C(C)(C)O)CC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.50
CYP3A4 P08684 2/20 0.39
ALOX15 P16050 2/20 0.39
STAT3 P40763 2/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
CHRNA7 P36544 1/20 0.39
TAS2R46 P59540 4/20 0.36
PTPN1 P18031 1/20 0.34
TAS2R31 P59538 2/20 0.32
TAS2R10 Q9NYW0 2/20 0.32
CES2 O00748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17867128 0.75 LMNA (0.45) LMNACYP3A4ALOX15STAT3MEN1
SCHEMBL17866753 0.70 LMNA (0.36) LMNA
Alpha-Terpineol SCHEMBL980991 0.68 LMNA (1.00) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL891812 0.68 LMNA (1.00) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL10925321 0.68 LMNA (1.00) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL901351 0.68 LMNA (1.00) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL28466 0.68 LMNA (1.00) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL9562893 0.66 LMNA (0.96) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL28134655 0.64 LMNA (0.89) LMNACYP3A4ALOX15STAT3MEN1
Alpha-Terpineol SCHEMBL28159391 0.62 LMNA (0.77) LMNACYP3A4ALOX15STAT3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed