SCHEMBL17867237

SCHEMBL17867237

CC(C)[C@H]1CC[C@]2(C)[C@H]3CC[C@@H]4[C@@]5(C)CCC(O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@@]12C

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC10A1 Q14973 1/20 0.55
GPBAR1 Q8TDU6 4/20 0.54
PRKCD Q05655 1/20 0.54
PTPN1 P18031 6/20 0.53
TOP2A P11388 2/20 0.49
PTPRF P10586 1/20 0.49
ACP1 P24666 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
NR1H4 Q96RI1 1/20 0.47
USP2 O75604 2/20 0.46
LMNA P02545 2/20 0.46
HIF1A Q16665 2/20 0.46
NT5E P21589 1/20 0.46
RELA Q04206 1/20 0.46
ALB P02768 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30939494 0.91 SLC10A1 (0.52) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL28453559 0.79 PTPN1 (0.67) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL29400217 0.79 PTPN1 (0.67) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL30901202 0.77 PTPN1 (0.53) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL476921 0.75 SLC10A1 (0.73) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL13384623 0.75 SLC10A1 (0.73) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL13403268 0.75 SLC10A1 (0.73) SLC10A1GPBAR1PRKCDPTPN1TOP2A
SCHEMBL476920 0.75 SLC10A1 (0.73) SLC10A1GPBAR1PRKCDPTPN1TOP2A
Tetrahymanol SCHEMBL1401904 0.75 PTPN1 (0.57) SLC10A1GPBAR1PRKCDPTPN1TOP2A
Tetrahymanol SCHEMBL5831685 0.75 PTPN1 (0.57) SLC10A1GPBAR1PRKCDPTPN1TOP2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed