Tetrahymanol

Tetrahymanol

SCHEMBL1401904

CC1(C)CCC[C@]2(C)[C@H]3CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]3(C)CC[C@@H]12

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 8/20 0.57
TOP2A P11388 2/20 0.49
HIF1A Q16665 2/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
GPBAR1 Q8TDU6 2/20 0.46
SLC10A1 Q14973 1/20 0.46
PTPRF P10586 1/20 0.46
ACP1 P24666 1/20 0.46
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
NT5E P21589 1/20 0.46
RELA Q04206 1/20 0.46
PRKCD Q05655 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahymanol SCHEMBL5831685 1.00 PTPN1 (0.57) PTPN1TOP2AHIF1ACES2CES1
SCHEMBL29501291 0.85 PTPN1 (0.68) PTPN1HIF1A
SCHEMBL17867180 0.81 PTPN1 (0.53) PTPN1TOP2AHIF1ACES2CES1
SCHEMBL18760924 0.81 PTPN1 (0.53) PTPN1TOP2AHIF1ACES2CES1
SCHEMBL16433264 0.80 PTPN1 (0.49) PTPN1HIF1APTPRFACP1RELA
SCHEMBL29400217 0.77 PTPN1 (0.67) PTPN1TOP2AHIF1ACES2CES1
SCHEMBL28453559 0.77 PTPN1 (0.67) PTPN1TOP2AHIF1ACES2CES1
Hopenol B SCHEMBL29985737 0.76 PTPN1 (0.69) PTPN1TOP2AHIF1ACES2CES1
Hopenol B SCHEMBL30036559 0.76 PTPN1 (0.69) PTPN1TOP2AHIF1ACES2CES1
SCHEMBL17867237 0.75 SLC10A1 (0.55) PTPN1TOP2AHIF1ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260009064-A1 STEROL PRODUCTION IN YEAST Apix Biosciences (BE) 2026-01-08 US claimed
WO-2023089317-A1 STEROL PRODUCTION IN YEAST OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-05-25 WO claimed
WO-2021133171-A1 RECOMBINANT FUNGAL CELL TECHNISCHE UNIVERSITEIT DELFT (NL) 2021-07-01 WO claimed
WO-2021072473-A1 ANTIMICROBIALS AS FEED PRESERVATIVES IRP Health Pty Ltd (AU) 2021-04-22 WO claimed
US-20030207317-A1 Novel nucleic acid isolated from Tetrahymena which codes for a triterpenoid cyclase, its production, and use RUSING MATTHIAS (DE) 2003-11-06 US claimed
US-20020031797-A1 Novel nucleic acid isolated from tetrahymena which codes for a triterpenoid cyclase, its production, and use NUTRINOVA, NUTRITION SPECIALTIES & FOOD (DE) 2002-03-14 US claimed
US-20260009064-A1 STEROL PRODUCTION IN YEAST Apix Biosciences (BE) 2026-01-08 US disclosed
EP-4608876-A2 ENDOCYTIC AGENTS BioVentures, LLC (US) 2025-09-03 EP disclosed
US-20240397979-A1 METHODS FOR DELIVERING BENEFICIAL NUTRIENTS TO INVERTEBRATES THROUGH A MICROORGANISM DEFICIENT IN ANTINUTRIENTS Apix Biosciences (BE) 2024-12-05 US disclosed
US-20240389618-A1 METHODS FOR DELIVERING 24-METHYLENE CHOLESTEROL, ISOFUCOSTEROL, CHOLESTEROL OR DESMOSTEROL TO INVERTEBRATES, IN PARTICULAR HONEY BEES OR BUMBLE BEES Apix Biosciences (BE) 2024-11-28 US disclosed
EP-4408190-A1 METHODS FOR DELIVERING 24-METHYLENE CHOLESTEROL, ISOFUCOSTEROL, CHOLESTEROL OR DESMOSTEROL TO INVERTEBRATES, IN PARTICULAR HONEY BEES OR BUMBLE BEES APIX BIOSCIENCES (BE) 2024-08-07 EP disclosed
WO-2024092274-A2 ENDOCYTIC AGENTS BIOVENTURES, LLC (US) 2024-05-02 WO disclosed
WO-2023089317-A1 STEROL PRODUCTION IN YEAST OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2023-05-25 WO disclosed
US-20030207317-A1 Novel nucleic acid isolated from Tetrahymena which codes for a triterpenoid cyclase, its production, and use RUSING MATTHIAS (DE) 2003-11-06 US disclosed
US-6534100-B1 Methods for treating cholesterol-containing foodstuffs using live ciliates VALCARCE GERMAN A (AR) 2003-03-18 US disclosed
EP-1251167-A2 Delta 7 and delta 22 cholesterol desaturases from ciliata phylum, and uses Valcarce, German A. (AR) 2002-10-23 EP disclosed
US-6391351-B2 REDUCING THE LEVEL OF CHOLESTEROL AND INCREASING DELTA 7 OR 22 DEHYDROCHOLESTEROL AND/OR DELTA 7, 22 BISDEHYDROCHOLESTEROL BY INCUBATION WITH FRACTIONS OF THE TETRAHYMENIDAE FAMILY VALCARCE GERMAN A (AR) 2002-05-21 US disclosed
US-20020031797-A1 Novel nucleic acid isolated from tetrahymena which codes for a triterpenoid cyclase, its production, and use NUTRINOVA, NUTRITION SPECIALTIES & FOOD (DE) 2002-03-14 US disclosed
US-20020009519-A1 Methods for treating foodstuffs using cell free extracts from ciliates VALCARCE GERMAN A (AR) 2002-01-24 US disclosed
WO-2001019201-A1 METHODS FOR TREATING CHOLESTEROL-CONTAINING FOODSTUFFS USING LIVE CILIATES FLORIN CHRISTENSEN JORGE (US) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260009064-A1 STEROL PRODUCTION IN YEAST SREBF2, ERG28, SREBF1 PTPN1 2240/4885TOP2A 3349/4885HIF1A 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.